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  • You will see a list of recommended treatments. You can select the one you prefer.
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  • Once you’ve completed the checkout, our doctors will review your answers. If all is safe, you will receive your treatment tomorrow.
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Available Treatment(s)
Wegovy 4.8 ( 441 Reviews)
  • Latest weight loss treatment
  • Once weekly injection
  • Reduces appetite
Prices start from £169.00 Prices and product information
Mounjaro 4.8 ( 130 Reviews)
  • Latest weight loss treatment
  • Once weekly injection
  • Reduces your appetite
Prices start from £179.99 Prices and product information
Box of Mysimba 8mg/90mg naltrexone/bupropion hydrochloride 112 prolonged-release tablets
Mysimba 4.6 ( 158 Reviews)
  • Effective weight loss treatment
  • Reduces appetite
  • Supports a healthy diet & exercise regime
Prices start from £109.99 Prices and product information
Box of 84 Orlistat 120mg hard capsules for oral use
Orlistat 4.6 ( 43 Reviews)
  • Same active ingredient as Xenical
  • Blocks up to 30% of fat intake
  • Clinically-proven results
Prices start from £34.99 Prices and product information
A pack of 84 Xenical® capsules contains 120mg of orlistat
Xenical 4.7 ( 130 Reviews)
  • Blocks up to 30% of fat intake
  • Clinically proven success
  • Supports a healthy diet & exercise regime
Prices start from £59.99 Prices and product information
Box containing 5 pre-filled pens Saxenda® 6mg/ml Liraglutide solution for injection
Saxenda 4.8 ( 677 Reviews)
  • Supports weight loss
  • One injection daily
  • Active ingredient: Liraglutide

Weight Loss

According to a recent NHS health survey, two-thirds of adults in the UK are overweight or obese. It’s a condition that puts you at a higher risk of health complications and significantly impacts your quality of life.

Losing weight is the best way to get a grasp on your health. Luckily, you no longer have to lose weight alone. Weight loss treatments, when combined with a healthy lifestyle, are the perfect tool to help you lose weight. HealthExpress offers several treatments, such as Mysimba, Xenical (Orlistat), Saxenda and Wegovy.

Topics

Medically reviewed by Dr. Plauto Filho Written by our editorial team Last reviewed 21-10-2024

Treatments summary

There are many factors to consider when determining which weight loss drug is best for you. Here is a helpful table showing all weight loss medications available and how they differ from each other.

Treatment Efficiency Potential Weight Loss How It Works Active Ingredient Usage Dosage Changes* Prices From:
Mounjaro Very high Up to 20% in 17 months Reduces appetite and increases energy use Tirzepatide Weekly injection Increases after 4 weeks £179.99
Wegovy High Up to 15% in 1 year Reduces appetite by slowing stomach emptying Semaglutide Weekly injection Increases monthly until month 4-5 £169.00
Saxenda Moderate Up to 11% in 1 year Reduces appetite by slowing stomach emptying Liraglutide Daily injection Increases weekly until reaching 3.0mg £69.99
Mysimba Moderate Up to 10% in 1 year Alters brain pathways to reduce appetite Bupropion & Naltrexone 1-4 tablets daily Increases weekly until week 4 £109.99
Xenical Moderate Up to 10% in 1 year Decreases fat absorption from food Orlistat Up to 3 capsules daily Remains the same £59.99

Deciding which treatment is right for you depends on many factors, but you don't have to decide alone. Start a consultation with HealthExpress today, and our doctors will assist you in selecting the appropriate treatment for your needs.

How does HealthExpress support me?

Losing weight for good means creating a healthy lifestyle. This might be the toughest part, but you don’t have to do it alone. Our multidisciplinary team of experts help you throughout your journey.

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Dietary advice and meal plans to help build long-term habits

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Exercise tips to add into your daily routine

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Follow-up consultations to check in with your journey

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Information about weight loss related topics

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Calorie tips to reduce them in a smart way

What is my ideal weight?

There is no one ideal weight for everyone. A healthy weight for you will depend on your background, height, and activity levels. However, one medical way to calculate what weight you should be is your BMI.

What is BMI?

Body Mass Index (BMI) is a way of calculating your ideal body weight based on your height. You calculate it by dividing your weight in kilograms by your height in meters squared (weight (kg) / (height (m))²). There are also several tools online that will calculate your BMI for you.

It is the method most used by clinical professionals and is what is used when deciding whether someone is suitable for treatment. However, it may not be accurate if you have a lot of muscle mass.

What does your BMI mean?

Your BMI will tell you whether your weight is within a healthy range or not. See the below BMI chart to see where your BMI fits.

Underweight

Underweight
below 18.5

Healthy weight

Healthy weight
18.5 to 24.9

Overweight

Overweight
25 to 29.9

Obese

Obese
30 to 39.9

If you have a BMI of 40 or more, you are deemed as morbidly obese.

What causes obesity?

Obesity is caused by eating more than you need. When you eat more than you need, your body stores the extra calories as fat. It can cause weight gain.

The availability of fast food is increasing, while the amount of physical activity people are doing is decreasing. This is causing a health crisis. 12% of British people say they eat fast food at least once a week.

What are the risk factors for obesity?

Some medical conditions, medicines and other factors are linked to weight gain, including:

  • old age
  • an underactive thyroid (hypothyroidism)
  • PCOS (polycystic ovary syndrome)
  • Cushing’s syndrome
  • menopause
  • hormonal contraceptives (e.g. the pill, mini-pill, patch or ring)
  • epilepsy medicines
  • steroids
  • antidepressants
  • quitting smoking

A common myth is that obesity is genetic and therefore losing weight is too difficult. However, this is not the case. While you may have inherited traits that mean you have a larger appetite and gain weight more easily, that doesn’t mean you cannot lose weight.

Can diabetes cause weight gain?

High blood sugar levels in people with diabetes can result in weight gain. This is because the excess sugar in the bloodstream causes insulin to be stored in the body as fatty tissue. People who take insulin may also see weight gain as a side effect.

Managing your diabetes, alongside healthy lifestyle changes, will help with weight loss as well as improve your health and well-being overall.

What are the risks of obesity?

Being overweight can cause physical and mental health problems. For example, it can lead to:

  • heart problems (e.g. heart disease, high blood pressure and high cholesterol)
  • breathing difficulties and respiratory conditions like asthma
  • type 2 diabetes
  • muscle, joint and bone problems
  • mental health problems
  • neurodegenerative disorders (e.g. Alzheimer’s)

Being obese can lead to life-threatening complications, such as heart attacks and strokes. It can also increase your risk of developing cancer, and it can make your life shorter by 3 to 10 years.

What are the benefits of weight loss?

Losing weight will significantly reduce your risk of serious health complications. Research has shown that it reduces your risk of 13 cancers, including bowel and breast cancer.

Not only does it improve your physical health, but it also has many other health benefits that will improve your general well-being.

  • It will boost your confidence and self-esteem.
  • It gives you the freedom to be more active, go out and do activities you may not necessarily have been able to do before.
  • It will improve your mental health.
  • You will save money on takeaways and fast food.
  • It will improve your sleep.
  • Your sex drive and abilities may improve.
  • It will give you more mental clarity, and improve memory and cognitive abilities overall.

The bottom line is that there are many good reasons to lose weight, not just for aesthetic reasons.

How can I lose weight?

For successful weight loss, you first need to make some simple but crucial lifestyle changes. You need to reduce your calorie intake and add some physical activity to your routine.

What should I eat to lose weight?

The key to weight loss is a low-calorie diet. The recommended calorie intake is 2,000kcal daily for women and 2,500kcal for men. So if you eat more than the recommended allowance daily, you’re more likely to gain weight.

As well as eating in a calorie deficit, you must eat the right foods.

A balanced diet includes plenty of:

  • fruits and vegetables
  • healthy fats (e.g. oily fish, olive oil, nuts and seeds)
  • lean proteins (e.g. chicken and turkey)
  • wholegrains (e.g oats, wholewheat pasta and bread)

While you should not overly restrict yourself, you should eat certain foods in moderation. Sweets and junk food are high in sugar and saturated fats are higher in calories and can lead to weight gain.

What is the best weight loss diet?

While a low-calorie diet works for most to lose weight, there are many popular diet plans for weight loss.

  • Keto diet / Atkins diet - A high-fat and low-carb diet designed to make the body burn fat for energy rather than sugars.
  • Intermittent fasting - Specific periods of time where you eat and fast.
  • DASH diet - Focuses on making healthier choices and eating more vegetables, fruits, whole grains and healthy fats.
  • Mediterranean diet - Similar to the DASH diet. Focuses on making better food choices except based on the diets of countries that board the Mediterranean Sea (e.g. Greece & Italy).

These diets can have benefits but are not safe for everyone. They can lead to unhealthy eating habits or side effects from dieting incorrectly. Always consult a healthcare or nutrition professional (e.g. a dietitian) before starting any diet.

Can you lose weight without dieting?

If you want to lose weight, you will need to change your diet. However, you don’t have to go on a radical diet or specific diet plan for sustainable weight loss. Instead, focus on consuming fewer calories and prioritising eating healthy foods.

Planning your meals and calorie counting will help to ensure you don’t exceed your daily calorie allowance.

What exercise is best for weight loss?

Boosting the amount of physical activity you do will also help with weight loss, as it will help burn the calories you consume.

Aim to do at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity physical activity each week. See below for examples of each.

Moderate-intensity Vigorous-intensity
  • brisk walking
  • cycling
  • dancing
  • pushing a lawn mower
  • hiking
  • running
  • swimming
  • walking up stairs
  • sports
  • skipping

You don’t have to do a lot to see results. Even walking at just 3 miles per hour for 30 minutes can burn up to 150 calories.

Why am I struggling to lose weight?

Achieving your goals is not easy, and it’s natural to reach a plateau or not see progress. If you’re not seeing progress, you may want to reevaluate your strategy.

Ask yourself several questions:

  • Are you eating the right foods? Remember, what you drink also contains calories.
  • Have you reduced your calories?
  • Have you gained muscle mass?
  • Are you exercising?
  • Are you getting enough sleep? Are you stressed?

These factors can hinder your journey. So while it might be disheartening to see the scale go down slowly, it’s important to take care of your well-being and your weight loss will happen gradually.

Tracking your progress through pictures is also a great way to stay motivated. You should also do regular measurements of your body. This is helpful if you’re exercising and trying to gain muscle mass because the scale may not go down but your measurements may change.

Do diet pills work?

As well as prescription injections and tablets, you may also come across other alternatives online. Diet supplements are available in the form of teas, drinks, gummies or powders and claim to help you lose weight with natural ingredients.

Unfortunately, these products tend to be fake. They can also be harmful to some people. Beware of any product that claims it will help you lose weight in a short space of time or by using natural ingredients because it probably doesn’t do what it says it does.

Never buy or use herbal supplements online without consulting a doctor or pharmacist.

How do I buy weight loss treatments online?

You can buy treatment online at HealthExpress, provided you are eligible for treatment. All you have to do is complete a confidential and quick online consultation so our doctors can ensure it's safe for you to take. Once approved, your treatment will be delivered to your doorstep with free next-day delivery.

Your safety is important to us, so our UK-registered doctors will closely monitor your progress throughout your weight loss program. This ensures you’re meeting your milestones.

Further reading

Find your perfect exercise: tips for every fitness level

Find your perfect exercise: tips for every fitness level

Reviewed by Dr. Plauto Filho
What are glucose spikes?

What are glucose spikes?

Reviewed by Dr. Plauto Filho
Does the DASH diet work for weight loss?

Does the DASH diet work for weight loss?

Reviewed by Dr. Plauto Filho
Understanding food cravings and how to tackle them

Understanding food cravings and how to tackle them

Reviewed by Dr. Plauto Filho
12 nutritionist tips to lose weight

12 nutritionist tips to lose weight

Reviewed by Dr. Plauto Filho
How many calories should I eat a day?

How many calories should I eat a day?

Reviewed by Dr. Plauto Filho
How can I stop feeling nauseous?

How can I stop feeling nauseous?

Reviewed by Dr. Plauto Filho
Walking and how it can help with weight loss

Walking and how it can help with weight loss

Reviewed by Dr. Plauto Filho
What should I eat to lose weight?

What should I eat to lose weight?

Reviewed by Dr. Plauto Filho
The benefits of exercise for weight loss

The benefits of exercise for weight loss

Reviewed by Dr. Plauto Filho
Obesity Statistics 2024: Facts and Figures in the UK

Obesity Statistics 2024: Facts and Figures in the UK

Reviewed by Dr. Plauto Filho
Wegovy interactions: what you need to know

Wegovy interactions: what you need to know

Reviewed by Dr. Plauto Filho
5 ways to increase weight loss on Wegovy

5 ways to increase weight loss on Wegovy

Reviewed by Dr. Plauto Filho
Ozempic weekly injection pen

Ozempic weekly injection pen

Reviewed by Dr. Plauto Filho
Side effects of Liraglutide and how to manage them

Side effects of Liraglutide and how to manage them

Reviewed by Dr. Plauto Filho
Semaglutide: what to expect and when

Semaglutide: what to expect and when

Reviewed by Dr. Plauto Filho
Semaglutide side effects: what you need to know

Semaglutide side effects: what you need to know

Reviewed by Dr. Plauto Filho
What semaglutide dose should I take?

What semaglutide dose should I take?

Reviewed by Dr. Plauto Filho
An introduction to GLP-1 agonists for weight loss

An introduction to GLP-1 agonists for weight loss

Reviewed by Dr. Plauto Filho
A guide to prescription weight loss treatments

A guide to prescription weight loss treatments

Reviewed by Dr. Plauto Filho
How do I administer injections for weight loss?

How do I administer injections for weight loss?

Reviewed by Dr. Caroline Fontana
Weight lifting for weight loss

Weight lifting for weight loss

Reviewed by Dr. Caroline Fontana
The best cardio exercises to lose weight

The best cardio exercises to lose weight

Reviewed by Dr. Caroline Fontana
Keto: does it really work for weight loss?

Keto: does it really work for weight loss?

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